Clinical neurophysiology practice · 2025
Efficacy of cerebellar cathodal transcranial direct current stimulation for post-stroke aphasia: A randomized controlled trial.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Xu Xiaoyi, Chen Shuping, Li Zifan, Zhang Lijie, Pan Tianjin, Long Siying, Yang Tingting, Li Meng, Li Qianru, Chen Na, Chen Shangjie, Zeng Qing
Аннотация
OBJECTIVE: Growing evidence highlights the cerebellum, particularly the right posterior lobule, in advanced language processes such as fluency, syntax, and phonological memory. However, its specific role in post-stroke aphasia recovery-especially its modulation of cortical networks and functional connectivity (FC)-remains unclear, which limits targeted intreventions.
METHODS: Sixteen post-stroke aphasia patients were randomized to receive either cerebellar transcranial direct current stimulation (tDCS) with speech therapy or sham stimulation with therapy. Language performance was assessed via the Chinese Standard Aphasia Scale (CRRCAE), and brain activation was monitored using functional near-infrared spectroscopy (fNIRS).
RESULTS: Both groups showed significant CRRCAE score improvements post-treatment (P < 0.05), without between-group differences (P > 0.05). FC reductions were noted across several interhemispheric and right-hemispheric pathways, while increased FC was observed in left hemisphere language-related areas.
CONCLUSION: After baseline adjustment, the intervention group showed superior gains. Cerebellar tDCS modulates FC, suggesting a potential mechanism for enhancing aphasia recovery.
SIGNIFICANCE: Findings support the cerebellum as a promising neuromodulation target for post-stroke aphasia treatment.
METHODS: Sixteen post-stroke aphasia patients were randomized to receive either cerebellar transcranial direct current stimulation (tDCS) with speech therapy or sham stimulation with therapy. Language performance was assessed via the Chinese Standard Aphasia Scale (CRRCAE), and brain activation was monitored using functional near-infrared spectroscopy (fNIRS).
RESULTS: Both groups showed significant CRRCAE score improvements post-treatment (P < 0.05), without between-group differences (P > 0.05). FC reductions were noted across several interhemispheric and right-hemispheric pathways, while increased FC was observed in left hemisphere language-related areas.
CONCLUSION: After baseline adjustment, the intervention group showed superior gains. Cerebellar tDCS modulates FC, suggesting a potential mechanism for enhancing aphasia recovery.
SIGNIFICANCE: Findings support the cerebellum as a promising neuromodulation target for post-stroke aphasia treatment.