Journal of hand surgery global online · 2026
Incidence of Carpal Tunnel Syndrome After the Diagnosis of Ulnar Neuropathy.
СтатьяНазвание и аннотация: Перевод в очереди
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Fellheimer Harrison S, DiDomenico Eric, Ayub Mahaa, Livingston Magnolia, Justice William L, Onor Gabriel I, Tecce Eric, Beredjiklian Pedro K
Аннотация
PURPOSE: The purpose of this study is to determine whether patients diagnosed with ulnar nerve lesions (UNLs) have an increased risk of developing carpal tunnel syndrome (CTS).
METHODS: A retrospective cohort study was conducted using the TriNetX database, which contains data of >100 million patients. We identified 360,021 patients with UNLs and matched them 1:1 with controls. The incidence of CTS was assessed at 1, 2, 3, 4, and 5 years following the diagnosis of UNL. Statistical analyses were used to evaluate the development of CTS in the UNL cohort compared with controls.
RESULTS: Patients with UNL demonstrated a significantly higher risk of developing CTS at all time points. At 1 year post-UNL diagnosis, the risk of CTS was 10.4% in the UNL group versus 3.1% in controls (P < .0001). This difference persisted throughout the 5-year period. Odds ratios similarly indicated a significantly greater likelihood of CTS development in patients with UNL.
CONCLUSIONS: Patients with a history of UNLs are at a significantly increased risk of developing CTS, especially within the first 2 years. This supports the hypothesis that ulnar nerve pathology may precede and increase susceptibility to median nerve compression.
TYPE OF STUDY/LEVEL OF EVIDENCE: Prognostic III.
METHODS: A retrospective cohort study was conducted using the TriNetX database, which contains data of >100 million patients. We identified 360,021 patients with UNLs and matched them 1:1 with controls. The incidence of CTS was assessed at 1, 2, 3, 4, and 5 years following the diagnosis of UNL. Statistical analyses were used to evaluate the development of CTS in the UNL cohort compared with controls.
RESULTS: Patients with UNL demonstrated a significantly higher risk of developing CTS at all time points. At 1 year post-UNL diagnosis, the risk of CTS was 10.4% in the UNL group versus 3.1% in controls (P < .0001). This difference persisted throughout the 5-year period. Odds ratios similarly indicated a significantly greater likelihood of CTS development in patients with UNL.
CONCLUSIONS: Patients with a history of UNLs are at a significantly increased risk of developing CTS, especially within the first 2 years. This supports the hypothesis that ulnar nerve pathology may precede and increase susceptibility to median nerve compression.
TYPE OF STUDY/LEVEL OF EVIDENCE: Prognostic III.