[Expert consensus on the clinical management of therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy (2026)].

Hypoxic-ischemic encephalopathy (HIE) is a major cause of neonatal death and long-term neurodevelopmental impairment. Therapeutic hypothermia is an effective intervention to improve the prognosis of neonates with moderate to severe HIE, and its standardized management is crucial for optimizing outcomes. Based on domestic and international evidence and expert opinion, the Evidence-Based Medicine Group, Neonatologist Society, Chinese Medical Doctor Association developed the "Expert consensus on the clinical management of therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy (2026)" using the Grading of Recommendations Assessment, Development, and Evaluation approach. The consensus focuses on 14 key clinical questions related to therapeutic hypothermia that are of concern to medical staff and formulates 22 recommendations. It aims to provide standardized and practical guidance and workflow for the clinical management of therapeutic hypothermia in neonates with HIE, promote integrated collaboration between physicians and nurses, and improve patient outcomes.