The Journal of craniofacial surgery · 2025
A Comparative Meta-Analysis of Microvascular Decompression and Microballoon Compression in the Treatment of Trigeminal Neuralgia.
СтатьяМетаанализСравнительное исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Wang Yungang, Zhang Zheying, Du Baoshun, Wang Lixiang, Han Guanzhe, Cheng Zhenguo
Аннотация
BACKGROUND: Frequent attacks of trigeminal neuralgia bring great pain to patients and affect their normal work and life. Microvascular decompression (MVD) and microballoon compression (PMC) are the 2 main surgical treatment methods for this disease; this study explored the comparison of the efficacy of the 2 methods by meta-analysis.
METHODS: The databases Pubmed, Embase, Ovid, CNKI, Clinicaltrials.gov , Google Scholar were searched, controlled studies of all 2 procedures since the establishment of the database were included, and after screening and risk of bias assessment, a meta-analysis was performed using Stata 16.0 software.
RESULTS: Eight literatures met the criteria and were included in the final meta-analysis, with a total of 916 participants. Meta-analysis showed that there was no significant difference in the postoperative pain relief rate between MVD and PMC [RR = 1.03, 95% CI (0.95, 1.12), Z = 0.760, P = 0.447], but the long-term pain relief rate of MVD surgery was higher than that of PMC [RR = 1.10, 95% CI (1.01, 1.19), Z = 2.210, P = 0.027], and the recurrence rate of MVD surgery was lower than that of PMC [RR = 0.62, 95% CI (0.40, 0.98), Z = -2.040, P = 0.041]; the incidence of postoperative facial dysesthesia complications using MVD was lower than that of PBC/PMC [RR = 0.26, 95% CI (0.17, 0.40), Z = -5.959, P = 0.000], the incidence of postoperative complications of masseter weakness was lower than that of PBC/PMC [RR = 0.20, 95% CI (0.04, 0.93), Z = -2.047, P = 0.041].
DISCUSSION: MVD is as effective as PMC surgery in relieving pain immediately after surgery in patients with trigeminal neuralgia, but MVD has a higher efficacy of long-acting pain relief than PMC, and has a lower recurrence rate than PMC.
METHODS: The databases Pubmed, Embase, Ovid, CNKI, Clinicaltrials.gov , Google Scholar were searched, controlled studies of all 2 procedures since the establishment of the database were included, and after screening and risk of bias assessment, a meta-analysis was performed using Stata 16.0 software.
RESULTS: Eight literatures met the criteria and were included in the final meta-analysis, with a total of 916 participants. Meta-analysis showed that there was no significant difference in the postoperative pain relief rate between MVD and PMC [RR = 1.03, 95% CI (0.95, 1.12), Z = 0.760, P = 0.447], but the long-term pain relief rate of MVD surgery was higher than that of PMC [RR = 1.10, 95% CI (1.01, 1.19), Z = 2.210, P = 0.027], and the recurrence rate of MVD surgery was lower than that of PMC [RR = 0.62, 95% CI (0.40, 0.98), Z = -2.040, P = 0.041]; the incidence of postoperative facial dysesthesia complications using MVD was lower than that of PBC/PMC [RR = 0.26, 95% CI (0.17, 0.40), Z = -5.959, P = 0.000], the incidence of postoperative complications of masseter weakness was lower than that of PBC/PMC [RR = 0.20, 95% CI (0.04, 0.93), Z = -2.047, P = 0.041].
DISCUSSION: MVD is as effective as PMC surgery in relieving pain immediately after surgery in patients with trigeminal neuralgia, but MVD has a higher efficacy of long-acting pain relief than PMC, and has a lower recurrence rate than PMC.