Retained Descemet's membrane after penetrating keratoplasty with previous Descemet's membrane endothelial keratoplasty.

Although keratoplasties are key surgical procedures for treating corneal diseases, they may present late complications such as retrocorneal membranes. We present an unusual case following a penetrating keratoplasty (PKP) in a patient with a history of DMEK. This is the case of an 85-year-old woman with a past medical history of DMEK and 2 PKPs due to previous graft failures, who developed a retrocorneal membrane 6 months after the last PKP. A membranectomy was performed. Histological analysis confirmed the presence of retained Descemet's membrane and decreased endothelial cell density. Visual acuity remained stable (0.4-0.63) with no signs of edema. No recurrence was observed. Late retention of Descemet's membrane may result from incomplete descemetorhexis, among other causes. Although asymptomatic, it may require surgery. Close postoperative follow-up is essential.