Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat · 2015
[Lipoid proteinosis (Urbach-Wiethe's Disease)].
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Karaman Hatice, Soyuer Işın, Külahcı İsmail, Tatlışen Nursen
Аннотация
A 25-year-old female patient was admitted to our outpatient clinic with postpartum hoarseness. Punch biopsy specimens obtained from the larynx and sublingual region revealed multi-folded squamous epithelium with a hyperkeratosis pattern and amorphous hyaline material aggregation. This aggregation was also remarkable around the vessels. Histochemical examination showed periodic acid-schiff-positive staining of the basal membrane with negative staining with Congo red. Physical examination revealed papule-like itchy lesions in the whole body and hoarseness. Ophthalmological examination showed bilateral blepharitis. Tooth loss and yellowish papule formation in the oral mucosa were remarkable. The patient was diagnosed with lipoid proteinosis characterized by typical vocal cord involvement and conventional histopathological and clinical findings.