The Journal of laryngology and otology · 2026
Risk of laryngopharyngeal reflux in Hubble Bubble smokers presenting with hoarseness.
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Hamdan Abdul Latif, Carapiperis Ibana, Ghzayel Lana, Lababidi Ghena, Sarkis Valerie, Hosri Jad, Zeineddine Nijad, Abou Raji Feghali Patrick
Аннотация
OBJECTIVES: This study aimed to investigate the risk of laryngopharyngeal reflux in Hubble Bubble smokers in comparison to non-smokers.
METHODS: The medical records of patients who presented with hoarseness were reviewed. Patients with a history of Hubble Bubble smoking and a control group of non-smokers were included in the study. The risk of laryngopharyngeal reflux was assessed using the Reflux Symptom Index and the Reflux Finding Score.
RESULTS: Eighty-six Hubble Bubble smokers and 86 controls were included in the study. There was a statistically significant difference in the mean RSI between the two subgroups (10.05 ± 8.27 vs. 5.05 ± 6.58; p < 0.001). Hubble Bubble smokers were 4.24 times more likely to have a Reflux Symptom Index score greater than 13 in comparison to non-smokers (odds ratio = 4.24; 95 per cent confidence interval: 1.97-9.14).
CONCLUSION: Hubble Bubble smoking increases the risk of laryngopharyngeal reflux by two-fold. A larger prospective study is needed to substantiate the association between Hubble Bubble smoking and laryngopharyngeal reflux.
METHODS: The medical records of patients who presented with hoarseness were reviewed. Patients with a history of Hubble Bubble smoking and a control group of non-smokers were included in the study. The risk of laryngopharyngeal reflux was assessed using the Reflux Symptom Index and the Reflux Finding Score.
RESULTS: Eighty-six Hubble Bubble smokers and 86 controls were included in the study. There was a statistically significant difference in the mean RSI between the two subgroups (10.05 ± 8.27 vs. 5.05 ± 6.58; p < 0.001). Hubble Bubble smokers were 4.24 times more likely to have a Reflux Symptom Index score greater than 13 in comparison to non-smokers (odds ratio = 4.24; 95 per cent confidence interval: 1.97-9.14).
CONCLUSION: Hubble Bubble smoking increases the risk of laryngopharyngeal reflux by two-fold. A larger prospective study is needed to substantiate the association between Hubble Bubble smoking and laryngopharyngeal reflux.