Pyogenic Granuloma of the Retina: A Case Series.

AIM: To describe the clinicopathologic features of pyogenic granuloma (granulation tissue proliferation) extending from the retina.

METHODS

We describe 3 patients who underwent enucleation for endophthalmitis. The eyes were processed routinely for histopathologic examination.

RESULTS

All 3 enucleated eyes contained granulation tissue with reactive vascular channels and intervening stroma infiltrated with inflammatory cells. The vascular channels were arranged in a fan-like configuration and the tissue was classified as representing pyogenic granulomas.

CONCLUSIONS

Pyogenic granulomas (granulation tissue) may emanate from the retina in cases of endophthalmitis. This is distinct from neovascularization that may occur in proliferative diabetic retinopathy, central retinal vein occlusion, or other etiologies.