Journal of bodywork and movement therapies · 2025
The effectiveness of single-dose blinded platelet-rich plasma (PRP) vs. corticosteroid injection in mild-to-moderate carpal tunnel syndrome: A prospective, randomized, double blind study.
СтатьяРандомизированное исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Şenlikci Hüma Bölük, Afşar Sevgi İkbali, Coşar Sacide Nur, Kurtcebe Ali Niyazi, Özen Selin, Yemişçi Oya Ümit
Аннотация
BACKGROUND: Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy and patients suffer from nocturnal paresthesia, numbness, and weakness. The many different methods used in the treatment of CTS include physical therapy modalities, oral medication, exercises, or injections. However, no single method has been shown to be superior to others. The aim of this study was to evaluate the effectiveness in the relief of CTS symptoms of single-dose platelet-rich plasma injection (PRP) vs. corticosteorid (CS) injection.
MATERIAL AND METHODS: The study included 78 wrists of 59 female patients with mild to moderate CTS, who were randomly assigned to one of the two groups for a single dose PRP or CS injection. All the injections were administered by the same physician. Evaluations at the end of one and six months were performed by a different physician who was blinded to the groups. The patient evaluations were made using the Boston carpal tunnel questionnaire (BTCQ), grip strength, provocation tests and electrophysiological parameters.
RESULTS: No significant differences were determined between the groups in terms of BTCQ, grip strengths and provocation tests. All the electrophysiological parameters improved in the CS group, and all except amplitudes in the PRP group. Mid-long term (1st-6th month follow-up) improvements in velocities were observed only in the PRP group.
CONCLUSION: Platelet-rich plasma injection did not seem to be superior to CS injection.
CLINICAL TRIAL REGISTRATION: clinicaltrials. gov (NCT04000932).
MATERIAL AND METHODS: The study included 78 wrists of 59 female patients with mild to moderate CTS, who were randomly assigned to one of the two groups for a single dose PRP or CS injection. All the injections were administered by the same physician. Evaluations at the end of one and six months were performed by a different physician who was blinded to the groups. The patient evaluations were made using the Boston carpal tunnel questionnaire (BTCQ), grip strength, provocation tests and electrophysiological parameters.
RESULTS: No significant differences were determined between the groups in terms of BTCQ, grip strengths and provocation tests. All the electrophysiological parameters improved in the CS group, and all except amplitudes in the PRP group. Mid-long term (1st-6th month follow-up) improvements in velocities were observed only in the PRP group.
CONCLUSION: Platelet-rich plasma injection did not seem to be superior to CS injection.
CLINICAL TRIAL REGISTRATION: clinicaltrials. gov (NCT04000932).