Case reports in pathology · 2026
Collision of Hypopharyngeal Small-Cell Neuroendocrine Carcinoma and Laryngeal Squamous Cell Carcinoma at the Aryepiglottic Fold: Case Report and Review of Literature.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Mladenovic Neda, Jakovljevic Sasa, Tomanovic Nada, Jovanovic Katarina, Radivojevic Nemanja, Kablar Djurdjina, Tomic Ana Marija
Аннотация
BACKGROUND: Collision tumors are neoplasms in which two histologically different and topographically independent tumors are joined within the same mass. The aim of this paper is to present a rare case of collision carcinoma of the larynx (squamous cell and small-cell neuroendocrine carcinoma).
CASE REPORT—DIAGNOSIS/TREATMENT: A 72-year-old patient was reported to our clinic because of hoarseness, dyspnea, and dysphagia. Neck CT showed a right-sided laryngeal tumor. The patient underwent total laryngectomy, partial pharyngectomy, and right-sided thyroidectomy with bilateral selective neck dissection. A clear collision of two morphologically and immunohistochemically different components of the tumor was seen on the sections sampled from the aryepiglottic fold.
CONCLUSIONS: This case highlights the critical importance of obtaining multiple samples during tumor biopsy and emphasizes the role of detailed immunohistochemical staining. Considering the differences in histology, it is difficult to propose guidelines for treatment of these cancers.
CASE REPORT—DIAGNOSIS/TREATMENT: A 72-year-old patient was reported to our clinic because of hoarseness, dyspnea, and dysphagia. Neck CT showed a right-sided laryngeal tumor. The patient underwent total laryngectomy, partial pharyngectomy, and right-sided thyroidectomy with bilateral selective neck dissection. A clear collision of two morphologically and immunohistochemically different components of the tumor was seen on the sections sampled from the aryepiglottic fold.
CONCLUSIONS: This case highlights the critical importance of obtaining multiple samples during tumor biopsy and emphasizes the role of detailed immunohistochemical staining. Considering the differences in histology, it is difficult to propose guidelines for treatment of these cancers.