[Efficacy of modified endoscopic holmium laser-yellow zebra guidewire loop combined lithotripsy for giant refractory gastric bezoars].

A retrospective analysis was conducted on the clinical data of patients with giant refractory gastric bezoars treated at Zhongda Hospital of Southeast University between January 2019 and May 2025. All patients underwent modified endoscopic holmium laser-yellow zebra guidewire loop combined lithotripsy. Follow-up gastroscopy was performed 4 weeks postoperatively to analyze the efficacy of this combined technique in treating giant refractory gastric bezoars. A total of 38 patients were included, including 14 males and 24 females, aged (66±12) years (44-88 years). Thirty-five patients successfully achieved bezoar removal after a single treatment session, with a single-session success rate of 92.1% (35/38). Postoperative complications, such as nausea, vomiting, gastric mucosal injury, or pain, occurred in 4 patients (10.5%). At the 4-week follow-up gastroscopy, the complete ulcer healing rate was 87.0% (20/23). The modified endoscopic holmium laser-yellow zebra guidewire loop combined lithotripsy is a safe and effective treatment for giant refractory gastric bezoars.