RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin · 2026
Analysis of non-coronary findings in coronary CT angiography: differences in gender, age, location, and clinical significance in the Turkish population.
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Isik Muhammet İkbal, Taşar Mustafa
Аннотация
PURPOSE: The increasing use of coronary CT angiography (CCTA) in the diagnosis of coronary artery disease (CAD) necessitates the evaluation of non-coronary findings (NCFs) and the investigation of the origin of patients' symptoms. This study aims to analyze NCFs detected in patients undergoing CCTA for suspected CAD.
MATERIALS AND METHODS: The study retrospectively evaluated a total of 1503 patients who underwent CCTA procedures at our clinic between January 2020 and January 2024. All images were evaluated visually by a single reader. No automated detection system was used. Benign conditions, anatomical variations, and all findings deemed to require follow-up or treatment within the imaging field were noted. NCFs identified in the CCTA examinations were analyzed based on patients' gender and age, NCF location, and clinical significance (no/mild, moderate, and severe).
RESULTS: At least one NCF was identified in 1460 out of 1503 patients (97.2%), with a total of 7822 NCFs detected. 45.4% of the patients (n=682) were male and 54.6% (n=821) were female. The median age was found to be 52 [19-87] years for males and 57 [22-84] years for females. The most common NCFs observed in all patients were, respectively, spinal degenerative changes (65.4%, n=983), parenchymal bands-subpleural lines (47.2%, n=709), increased CTR (41.4%, n=622), hiatal hernia (36.7%, n=552), and esophageal thickening (30.9%, n=464). Certain NCFs, including nodules >8 mm (p=0.007), hiatal hernia (p=0.027), pulmonary artery dilatation (p=0.048), breast lesions (p=0.010), hyperdense liver lesions (p=0.024), and adrenal gland thickening (p=0.035), showed statistically significant differences between genders. Among NCFs, only scoliosis and age were found to have a significant but weak negative correlation (p<0.048, r=-0.051). The most common findings of no/mild, moderate, and severe clinical significance were spinal degenerative changes (n=983), thoracic aortic calcification (n=622), and pulmonary parenchymal infiltration (n=78), respectively.
CONCLUSION: Awareness of the variability in the distribution of NCFs based on age, gender, location, and clinical significance is crucial when evaluating CCTA scans performed for suspected CAD.
KEY POINTS: · NCFs vary according to gender, location, and clinical severity.. · Symptoms caused by NCFs can be confused with cardiac symptoms, leading to further investigations such as CCTA.. · The frequency and potential clinical significance of NCFs necessitate a holistic evaluation of CCTA..
CITATION FORMAT: · Isik Mİ, TAŞAR M. Analysis of non-coronary findings in coronary CT angiography: differences in gender, age, location, and clinical significance in the Turkish population. Rofo 2026; 10.1055/a-2826-0659.
MATERIALS AND METHODS: The study retrospectively evaluated a total of 1503 patients who underwent CCTA procedures at our clinic between January 2020 and January 2024. All images were evaluated visually by a single reader. No automated detection system was used. Benign conditions, anatomical variations, and all findings deemed to require follow-up or treatment within the imaging field were noted. NCFs identified in the CCTA examinations were analyzed based on patients' gender and age, NCF location, and clinical significance (no/mild, moderate, and severe).
RESULTS: At least one NCF was identified in 1460 out of 1503 patients (97.2%), with a total of 7822 NCFs detected. 45.4% of the patients (n=682) were male and 54.6% (n=821) were female. The median age was found to be 52 [19-87] years for males and 57 [22-84] years for females. The most common NCFs observed in all patients were, respectively, spinal degenerative changes (65.4%, n=983), parenchymal bands-subpleural lines (47.2%, n=709), increased CTR (41.4%, n=622), hiatal hernia (36.7%, n=552), and esophageal thickening (30.9%, n=464). Certain NCFs, including nodules >8 mm (p=0.007), hiatal hernia (p=0.027), pulmonary artery dilatation (p=0.048), breast lesions (p=0.010), hyperdense liver lesions (p=0.024), and adrenal gland thickening (p=0.035), showed statistically significant differences between genders. Among NCFs, only scoliosis and age were found to have a significant but weak negative correlation (p<0.048, r=-0.051). The most common findings of no/mild, moderate, and severe clinical significance were spinal degenerative changes (n=983), thoracic aortic calcification (n=622), and pulmonary parenchymal infiltration (n=78), respectively.
CONCLUSION: Awareness of the variability in the distribution of NCFs based on age, gender, location, and clinical significance is crucial when evaluating CCTA scans performed for suspected CAD.
KEY POINTS: · NCFs vary according to gender, location, and clinical severity.. · Symptoms caused by NCFs can be confused with cardiac symptoms, leading to further investigations such as CCTA.. · The frequency and potential clinical significance of NCFs necessitate a holistic evaluation of CCTA..
CITATION FORMAT: · Isik Mİ, TAŞAR M. Analysis of non-coronary findings in coronary CT angiography: differences in gender, age, location, and clinical significance in the Turkish population. Rofo 2026; 10.1055/a-2826-0659.