Histopathological insights of a rare tubal adenomatoid tumor - case report and literature review.

BACKGROUND

Adenomatoid tumors (ATs) of the Fallopian tube are rare benign neoplasms, accounting for approximately 0.5-1% of all ATs of the female genital tract. They are often asymptomatic and discovered incidentally. Due to their mesothelial origin, histopathological (HP) diagnosis may be uncertain, requiring immunohistochemical (IHC) tests for definitive confirmation.

CASE PRESENTATION: We present a case of an incidentally discovered tubal AT following a total hysterectomy with prophylactic salpingectomy in a 42-year-old patient with known uterine leiomyomatosis. IHC tests showed positive expression for calretinin and Wilms tumor 1 (WT1) and negative expression for Ki67 and p53, confirming the histological diagnosis of a tubal AT and ruling out malignancy.

CONCLUSIONS

This study highlights the asymptomatic nature of tubal ATs and emphasizes that they do not require specific treatment, and surgical excision is sufficient. Their HP appearance, combined with IHC findings, remains the key to diagnosis.