Indian journal of psychiatry · 2025
Untangling late-onset first-episode mania: A case series.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Khandelwal Harsh, Tyagi Sanyam, Kaur Harmanpreet, Verma Vishal, Nebhinani Naresh, Suthar Navratan, Gehlawat Pratibha
Аннотация
BACKGROUND: Late-onset bipolar disorder (LOB) presents unique diagnostic and management challenges as various symptom overlaps with neurocognitive disorders, medical comorbidities, and age-related physiological changes.
CASES: We report four elderly patients presenting with first-episode mania, highlighting clinical trajectories, comorbidities, and treatment responses. Three patients had metabolic comorbidities, while two had family history of psychiatric illness. Neuroimaging revealed small vessel ischemic changes in two cases, suggesting a vascular contribution. All patients required inpatient care and responded well to mood stabilizers and antipsychotics.
CONCLUSION: Further research is warranted to optimize management strategies for this understudied subset of bipolar disorder.
CASES: We report four elderly patients presenting with first-episode mania, highlighting clinical trajectories, comorbidities, and treatment responses. Three patients had metabolic comorbidities, while two had family history of psychiatric illness. Neuroimaging revealed small vessel ischemic changes in two cases, suggesting a vascular contribution. All patients required inpatient care and responded well to mood stabilizers and antipsychotics.
CONCLUSION: Further research is warranted to optimize management strategies for this understudied subset of bipolar disorder.