JACC. Case reports · 2026
From Nonobstructive Plaque to LAD Thrombosis in a 26-Year-Old Athlete.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Abu Zalam Mohammad, Kholeif Zeyad, Afzaal Usama, Khan Mustafa Dilawar, Patri Rahul
Аннотация
BACKGROUND: Stimulants and anabolic steroids have a role in plaque disruption resulting in acute coronary syndrome in young adults.
CASE SUMMARY: A 26-year-old bodybuilder with heavy use of anabolic steroids and energy drinks presented with chest pain and ST-segment changes. Coronary angiography revealed minimal nonobstructive plaque in the proximal left anterior descending artery and left ventricular systolic dysfunction. He was started on guideline-directed medical therapy and counseled to discontinue toxic exposures. Weeks later, he presented with recurrent chest pain and was found to have an acute thrombotic occlusion of the mid-left anterior descending artery requiring urgent revascularization and a drug-eluting stent placement.
DISCUSSION: This case highlights how synergistic stimulant and anabolic exposure can create dynamic coronary pathology and contribute to endothelial injury, hypercoagulability, and accelerated atherosclerosis.
TAKE-HOME MESSAGES: Nonobstructive coronary findings do not exclude imminent coronary thrombosis in high-risk young adults. Risk factor cessation and close follow-up are essential.
CASE SUMMARY: A 26-year-old bodybuilder with heavy use of anabolic steroids and energy drinks presented with chest pain and ST-segment changes. Coronary angiography revealed minimal nonobstructive plaque in the proximal left anterior descending artery and left ventricular systolic dysfunction. He was started on guideline-directed medical therapy and counseled to discontinue toxic exposures. Weeks later, he presented with recurrent chest pain and was found to have an acute thrombotic occlusion of the mid-left anterior descending artery requiring urgent revascularization and a drug-eluting stent placement.
DISCUSSION: This case highlights how synergistic stimulant and anabolic exposure can create dynamic coronary pathology and contribute to endothelial injury, hypercoagulability, and accelerated atherosclerosis.
TAKE-HOME MESSAGES: Nonobstructive coronary findings do not exclude imminent coronary thrombosis in high-risk young adults. Risk factor cessation and close follow-up are essential.