"Target Sign" of Schwannoma on Contrast-Enhanced Ultrasound.

This case series investigates the "Target sign" in contrast-enhanced ultrasound (CEUS) of 11 pathologically confirmed schwannomas, characterized by early central hyperenhancement (mean TTP: 15.7 ± 3.2 s) surpassing peripheral regions (19.1 ± 2.8 s). CEUS demonstrated 100% detection of this sign, outperforming grayscale ultrasound (45%), correlating with histologic Antoni A (cellular) and B (myxoid) areas. Findings suggest CEUS improves diagnostic specificity for schwannomas, offering non-invasive microvascular mapping. Limitations include small sample size and retrospective design.