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Travel medicine and infectious disease · 2025

Landscape of guidance documents used at TropNet and GeoSentinel centres for the clinical management of schistosomiasis outside endemic areas: A systematic appraisal.

СтатьяПоддержка исследования: вне правительства СШАПоддержка службы здравоохранения СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Tamarozzi Francesca, Mazzi Cristina, Antinori Spinello, Arsuaga Marta, Becker Sören L, Bocanegra Cristina, Bottieau Emmanuel, Buonfrate Dora, Bustinduy Amaya L, Camprubí-Ferrer Daniel, Caumes Eric, Duvignaud Alexandre, Grobusch Martin P, Huits Ralph, Jaureguiberry Stephane, Jordan Sabine, Mueller Andreas, Ndao Momar, Neumayr Andreas, Perez-Molina Jose A, Pettersen Frank O, Rothe Camilla, Salas-Coronas Joaquin, Salvador Fernando, Stothard J Russell, Tomasoni Lina R, van Hellemond Jaap J, van Lieshout Lisette, Vaughan Stephen D, Wammes Linda J, Yansouni Cedric P, Zammarchi Lorenzo, Gobbi Federico G

Аннотация

BACKGROUND: The diagnostic and treatment approaches for schistosomiasis in individual patients, outside endemic areas, are not standardised. This study aimed to appraise the reference documents that the experts from the TropNet and GeoSentinel networks use in practice as guidance for the clinical management of their patients with (suspect) schistosomiasis.

METHODS: We systematically appraised the following data from the referenced guidance documents: i) document type, ii) case definitions, iii) diagnostic techniques envisaged; iv) treatment recommendations; v) follow-up recommendations; vi) screening recommendations, and vii) symptom-based diagnostic suspicion.

RESULTS: Twenty-two of the 30 responders (73.3 %) indicated 19 reference documents, three of which were WHO material not intended for individual clinical management. Only 4/19 (21.1 %) documents were national recommendations; no international guideline was indicated. Case definitions were explicitly presented in only one document (1/19; 5.3 %). Diagnostic tools were detailed in 11/16 (68.8 %) and follow-up guidance in 8/16 (50 %) documents. Treatment guidance was provided in 14/16 (87.5 %) documents.

CONCLUSIONS: Heterogeneity in clinical guidance was evident, although with noticeable overlap at least for chronic schistosomiasis. This confirms the need to formalise case definitions, which should be used to design trials to rigorously assess diagnostic tools and treatment schemes, and eventually come to harmonization of clinical management guidance.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты