Wiadomosci lekarskie (Warsaw, Poland : 1960) · 2024
Follow-up performance of patients with cutaneous melanoma: recommendations for an effective strategy.
СтатьяНазвание и аннотация: Перевод в очереди
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Oshyvalova Olena O, Mazurenko Serhii M, Voinov Ivan G
Аннотация
OBJECTIVE: Aim: To investigate the incidence of progression and median time for metastasizing, the development of recurrent localization, and to identify localizations with a high tendency to recurrence of melanoma during 10 years of patient follow-up observation.
PATIENTS AND METHODS: Materials and Methods: The retrospective data of dynamic observation by dermatovenereologists of SIS ≪CIHT≫ SAD of 183 patients with skin melanoma for the period 2014 - first half of 2024.
RESULTS: Results: Among 183 cases of melanoma, 23 cases (12,6%) were detected in stage III and 11 cases (6,0%) in stage IV, so the neglect rate was 18,6%. Melanoma progression was detected in 39 patients (21,4%) after an average of (mean ±m) 5,3±1,8 years of follow-up, including 9 patients (23,1%) with stages I-II melanoma and all patients (30 people - 76,9%) with neglected cases (stages III-IV). In our study, the predominant localization of primary melanoma on the skin of the lower limbs (52,9%) and trunk (29,3%) resulted in further progression of the disease in the first 5-6 years of patients' follow-up.
CONCLUSION: Conclusions: Our study has supplemented the scientific data on the timing of follow-up of patients with skin melanoma and possible progression factors (tumour thickness, lymph node involvement, localization of the primary tumour), which should be taken into account in the dynamic monitoring of patients in order to detect disease progression timely.
PATIENTS AND METHODS: Materials and Methods: The retrospective data of dynamic observation by dermatovenereologists of SIS ≪CIHT≫ SAD of 183 patients with skin melanoma for the period 2014 - first half of 2024.
RESULTS: Results: Among 183 cases of melanoma, 23 cases (12,6%) were detected in stage III and 11 cases (6,0%) in stage IV, so the neglect rate was 18,6%. Melanoma progression was detected in 39 patients (21,4%) after an average of (mean ±m) 5,3±1,8 years of follow-up, including 9 patients (23,1%) with stages I-II melanoma and all patients (30 people - 76,9%) with neglected cases (stages III-IV). In our study, the predominant localization of primary melanoma on the skin of the lower limbs (52,9%) and trunk (29,3%) resulted in further progression of the disease in the first 5-6 years of patients' follow-up.
CONCLUSION: Conclusions: Our study has supplemented the scientific data on the timing of follow-up of patients with skin melanoma and possible progression factors (tumour thickness, lymph node involvement, localization of the primary tumour), which should be taken into account in the dynamic monitoring of patients in order to detect disease progression timely.