Echocardiography (Mount Kisco, N.Y.) · 2026
Prognostic Value of Preoperative Left Ventricular End-Diastolic Dimension in Patients With Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Implantation With the Venus-A Valve.
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Mei Baiqiang, Xu Zhaoyan, Li Jian, Cen Jinming, Wu Xuefeng, Wang Fei, Zheng Xueqin, Mo Zhan, Wu Yangfan, Chen Huomei, Li Weijie, Chen Lihong
Аннотация
OBJECTIVE: Severe aortic stenosis (AS) leads to chronic pressure overload of the left ventricle (LV). We explored the prognostic value of preoperative left ventricular end-diastolic dimension (LVEDD) dilation in patients with severe AS.
METHODS: This is a retrospective study of 108 patients with severe AS who underwent transcatheter aortic valve implantation with the Venus-A valve. These participants were assigned to the large LVEDD and non-large LVEDD groups. The receiver operating characteristic and Kaplan-Meier curves were generated to assess the predictive value of preoperative LVEDD dilation for poor patient prognosis (readmission or death within 1 year postoperatively), as well as its effects on the readmission risk owing to heart failure, and complications and survival rates within 1 year postoperatively.
RESULTS: Significant differences were observed between the two groups in B-type natriuretic peptide, creatinine, aortic valve area, transfemoral access, aortic valve peak velocity, mean transvalvular pressure gradient, LVEDD, left ventricular end-systolic dimension, left atrial dimension, interventricular septal thickness, relative wall thickness, left ventricular mass index, left ventricular ejection fraction, E/A ratio, E/e' ratio, and stroke volume index. Preoperative LVEDD dilation showed a predictive value for poor patient prognosis (AUC = 0.843; 95%CI: 0.761-0.906, 50.9 mm cut-off value, 99.9% sensitivity, 62.07% specificity). Preoperative LVEDD dilation was an independent influencing factor for poor prognosis within 1 year postoperatively, associated with increased readmission risk and reduced patient survival rate.
CONCLUSION: Preoperative LVEDD dilation is an independent influencing factor for poor postoperative prognosis in patients. It helps predict poor prognosis within 1 year postoperatively.
METHODS: This is a retrospective study of 108 patients with severe AS who underwent transcatheter aortic valve implantation with the Venus-A valve. These participants were assigned to the large LVEDD and non-large LVEDD groups. The receiver operating characteristic and Kaplan-Meier curves were generated to assess the predictive value of preoperative LVEDD dilation for poor patient prognosis (readmission or death within 1 year postoperatively), as well as its effects on the readmission risk owing to heart failure, and complications and survival rates within 1 year postoperatively.
RESULTS: Significant differences were observed between the two groups in B-type natriuretic peptide, creatinine, aortic valve area, transfemoral access, aortic valve peak velocity, mean transvalvular pressure gradient, LVEDD, left ventricular end-systolic dimension, left atrial dimension, interventricular septal thickness, relative wall thickness, left ventricular mass index, left ventricular ejection fraction, E/A ratio, E/e' ratio, and stroke volume index. Preoperative LVEDD dilation showed a predictive value for poor patient prognosis (AUC = 0.843; 95%CI: 0.761-0.906, 50.9 mm cut-off value, 99.9% sensitivity, 62.07% specificity). Preoperative LVEDD dilation was an independent influencing factor for poor prognosis within 1 year postoperatively, associated with increased readmission risk and reduced patient survival rate.
CONCLUSION: Preoperative LVEDD dilation is an independent influencing factor for poor postoperative prognosis in patients. It helps predict poor prognosis within 1 year postoperatively.