The Journal of dermatological treatment · 2026
Sociodemographic, clinical, and behavioral determinants of treatment adherence in acne vulgaris: a multicenter study.
СтатьяМногоцентровое исследованиеНазвание и аннотация: Перевод в очереди
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Ferhatosmanoğlu Arzu, Arıca İbrahim Etem, Polat Mualla, Yıldırım Mehmet, Kalkan Göknur, Başara Şahin Rana, Tosun Mustafa, Meral Elif Nur, Afacan Yıldırım Elif, Akpınar Kara Yeşim, Aksoy Saraç Gülhan, Bal Avcı Elif, Canat Harbiye Dilek, İlhan Erdil Dilara, İnan Yüksel Esma, Kartal Selda Pelin, Kaya Özden Hatice, Külcü Çakmak Seray, Tümtürk Mustafa, Yıldırım Yasemin Aygül, Karadağ Ayşe Serap
Аннотация
BACKGROUND: This multicenter study aimed to evaluate treatment adherence and satisfaction among patients with acne vulgaris.
METHODS: A total of 2,349 patients from 18 dermatology centers across Türkiye completed structured questionnaires.
RESULTS: The participants were predominantly female (79.4%) with a mean age of 21.6 years. Overall, 48% reported consistent adherence to therapy, with significantly lower adherence among males (p < 0.001). The most frequent reasons for nonadherence were forgetfulness (28.7%), dislike of the treatment (26.4%), and reluctance to maintain long-term therapy (21.5%). Treatment adherence was positively associated with higher educational levels (p = 0.006) and greater acne severity (p < 0.001). Logistic regression revealed that systemic oral therapy (OR = 4.37, 95% CI: 3.147-6.086; p < 0.001) and oral isotretinoin (OR = 4.81, 95% CI: 3.379-6.869; p < 0.001) significantly increased adherence compared to topical therapy. Oral treatment was also independently associated with greater satisfaction (OR = 2.33, 95% CI: 1.767-3.095; p < 0.001). Moreover, mild acne severity (OR = 1.67, 95% CI: 1.216-2.297; p = 0.002) and older age (per year; OR = 1.05, 95% CI: 1.020-1.088; p = 0.001) predicted higher satisfaction.
CONCLUSION: Systemic therapies-particularly oral isotretinoin-were associated with improved adherence and satisfaction.
METHODS: A total of 2,349 patients from 18 dermatology centers across Türkiye completed structured questionnaires.
RESULTS: The participants were predominantly female (79.4%) with a mean age of 21.6 years. Overall, 48% reported consistent adherence to therapy, with significantly lower adherence among males (p < 0.001). The most frequent reasons for nonadherence were forgetfulness (28.7%), dislike of the treatment (26.4%), and reluctance to maintain long-term therapy (21.5%). Treatment adherence was positively associated with higher educational levels (p = 0.006) and greater acne severity (p < 0.001). Logistic regression revealed that systemic oral therapy (OR = 4.37, 95% CI: 3.147-6.086; p < 0.001) and oral isotretinoin (OR = 4.81, 95% CI: 3.379-6.869; p < 0.001) significantly increased adherence compared to topical therapy. Oral treatment was also independently associated with greater satisfaction (OR = 2.33, 95% CI: 1.767-3.095; p < 0.001). Moreover, mild acne severity (OR = 1.67, 95% CI: 1.216-2.297; p = 0.002) and older age (per year; OR = 1.05, 95% CI: 1.020-1.088; p = 0.001) predicted higher satisfaction.
CONCLUSION: Systemic therapies-particularly oral isotretinoin-were associated with improved adherence and satisfaction.