Journal of cosmetic dermatology · 2026
Safety and Preliminary Clinical Effects of a Herbal Balance Solution in Mild-To-Moderate Acne Vulgaris: An Open-Label, Single-Arm Pilot Study.
СтатьяКлиническое исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Teng Xiaoyue, Shu Xiaohong, Huo Wei, Li Zhaoxia, Zou Lin, Li Li, Wang Xi
Аннотация
OBJECTIVE: Acne is a common skin condition that seriously affects the physical and mental health of patients. In addition to the standard acne treatment, anti-acne skin care products are gradually becoming essential in preventing and treating acne. Herbal Balance Solution contains multiple botanical ingredients with potential anti-inflammatory and barrier-supportive properties. This pilot study aimed to explore the safety and preliminary clinical effects of Herbal Balance Solution in patients with mild-to-moderate acne vulgaris.
METHODS: Thirty-three patients with mild or moderate acne vulgaris were treated with Herbal Balance Solution once every 3 days for 4 weeks. At baseline (Week 0, W0), Week 2 (W2), and Week 4 (W4), acne lesion counts (total, inflammatory, and non-inflammatory lesions) and the severity index were measured to assess the treatment efficacy, and transepidermal water loss was tested to assess face irritation.
RESULTS: The number of closed comedones was significantly reduced (p < 0.01) at each time point after using the test product. Furthermore, the transepidermal water loss rate significantly decreased (p < 0.05). At Week 4, reductions in total inflammatory and non-inflammatory lesion counts were observed and were statistically significant (p < 0.05).
CONCLUSION: In this open-label pilot study, use of Herbal Balance Solution was associated with short-term improvements in acne-related clinical parameters and skin barrier function and was well tolerated in patients with mild-to-moderate acne vulgaris. These preliminary findings warrant confirmation in randomized, vehicle-controlled clinical trials.
METHODS: Thirty-three patients with mild or moderate acne vulgaris were treated with Herbal Balance Solution once every 3 days for 4 weeks. At baseline (Week 0, W0), Week 2 (W2), and Week 4 (W4), acne lesion counts (total, inflammatory, and non-inflammatory lesions) and the severity index were measured to assess the treatment efficacy, and transepidermal water loss was tested to assess face irritation.
RESULTS: The number of closed comedones was significantly reduced (p < 0.01) at each time point after using the test product. Furthermore, the transepidermal water loss rate significantly decreased (p < 0.05). At Week 4, reductions in total inflammatory and non-inflammatory lesion counts were observed and were statistically significant (p < 0.05).
CONCLUSION: In this open-label pilot study, use of Herbal Balance Solution was associated with short-term improvements in acne-related clinical parameters and skin barrier function and was well tolerated in patients with mild-to-moderate acne vulgaris. These preliminary findings warrant confirmation in randomized, vehicle-controlled clinical trials.