[Determination of antituberculous antibodies in the cerebrospinal fluid by an immunoenzyme assay method in patients with tuberculous meningitis].

Possibilities of using enzyme immunoassay to identify specific antibodies to M. tuberculosis in the cerebrospinal fluid of 44 patients with tuberculous meningitis and 81 cases with other diseases of the central nervous system were analysed. The assay sensitivity and specificity in an active period of tuberculous meningitis made up 100 and 97.5%, respectively. The findings permit one to recommend the enzyme immunoassay for an early diagnosis of tuberculous meningitis.