Extensive, Multifocal Pott Disease in a United States-Born Veteran Without Human Immunodeficiency Virus.

Mycobacterium tuberculosis can infect the native vertebral body and nearby structures to cause tuberculous spondylodiscitis, also known as Pott disease. We present a case of extensive, multifocal Pott disease in a United States-born veteran without human immunodeficiency virus. We briefly comment on when to consider Pott disease in cases of vertebral osteomyelitis. We also discuss treatment considerations for Pott disease with and without tuberculous involvement of the central nervous system, the recognition of tuberculosis-associated immune reconstitution inflammatory syndrome, and certain indications for surgery in Pott disease.