European radiology · 2025
Can a low b-value diffusion-weighted imaging sequence replace the standard T2-weighted fluid-sensitive sequence in breast MRI? A single-center prospective study.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Gatewood Jason, Peterson Jessica, Aripoli Allison, Huppe Ashley, Winblad Onalisa, Walter Carissa, Young Kate, Li Yanming, Clark Lauren, Deshpande Vibhas, Itriago Pedro, Pinker Katja
Аннотация
OBJECTIVES: To determine whether a low b-value (b0) diffusion-weighted imaging (DWI) sequence of a similar acquisition time can fulfill the role of a T2-weighted/fluid-sensitive short tau inversion recovery (STIR) sequence.
MATERIALS AND METHODS: In this prospective, single-institutional study, participants underwent 3-T or 1.5-T breast MRI, which included a standard T2-weighted/fluid-sensitive short TI inversion recovery (STIR) sequence and an investigational DWI sequence (comprising readout segmented echo planar imaging (rs-EPI) and simultaneous multi-slice (SMS) imaging). Five radiologists independently scored 121 lesions on imaging by answering three questions assessing lesion conspicuity, lesion signal characteristics, and artifact grading. Statistical analysis included one-sample tests of proportions and Nelson's model kappa.
RESULTS: From 605 assessments in 72 patients (mean age, 48.3 ± 12.5 years [standard deviation]; 72 women), 537 (88.8%, p < 0.001) received assessments that lesion conspicuity on DWI was not inferior to STIR, 586 (96.9%, p < 0.001) received assessments that DWI followed the lesion signal characteristics on STIR, and 595 (98.3%, p < 0.001) received assessments that there were no or mild artifacts on DWI. Inter-reader agreement was substantial for similar lesion conspicuity (89.9%, к = 0.790, 95% CI: 0.76-0.82) and similar lesion signal characteristics (95.7%, к = 0.733, CI 0.69-0.77) on DWI and STIR, and moderate for whether there was mild/no artifact vs. moderate/substantial artifact on DWI (97.2%, к = 0.515, CI: 0.29-0.75).
CONCLUSION: Low b-value DWI provides similar diagnostic capabilities as T2-weighted/fluid-sensitive STIR, with comparable lesion conspicuity and lesion signal characteristics and without significant artifacts.
KEY POINTS: Question Can diffusion-weighted imaging (DWI) be incorporated into clinical 1.5-T and 3-T breast MRI protocols without adding acquisition time? Findings The signal characteristics and conspicuity of breast lesions on low b-value (b0) DWI were not inferior compared with that on standard T2-weighted/fluid-sensitive imaging. Clinical relevance The incorporation of low b-value DWI can translate to improved cost-effectiveness and patient experience of breast MRI by reducing false-positives and reducing overall scan time.
MATERIALS AND METHODS: In this prospective, single-institutional study, participants underwent 3-T or 1.5-T breast MRI, which included a standard T2-weighted/fluid-sensitive short TI inversion recovery (STIR) sequence and an investigational DWI sequence (comprising readout segmented echo planar imaging (rs-EPI) and simultaneous multi-slice (SMS) imaging). Five radiologists independently scored 121 lesions on imaging by answering three questions assessing lesion conspicuity, lesion signal characteristics, and artifact grading. Statistical analysis included one-sample tests of proportions and Nelson's model kappa.
RESULTS: From 605 assessments in 72 patients (mean age, 48.3 ± 12.5 years [standard deviation]; 72 women), 537 (88.8%, p < 0.001) received assessments that lesion conspicuity on DWI was not inferior to STIR, 586 (96.9%, p < 0.001) received assessments that DWI followed the lesion signal characteristics on STIR, and 595 (98.3%, p < 0.001) received assessments that there were no or mild artifacts on DWI. Inter-reader agreement was substantial for similar lesion conspicuity (89.9%, к = 0.790, 95% CI: 0.76-0.82) and similar lesion signal characteristics (95.7%, к = 0.733, CI 0.69-0.77) on DWI and STIR, and moderate for whether there was mild/no artifact vs. moderate/substantial artifact on DWI (97.2%, к = 0.515, CI: 0.29-0.75).
CONCLUSION: Low b-value DWI provides similar diagnostic capabilities as T2-weighted/fluid-sensitive STIR, with comparable lesion conspicuity and lesion signal characteristics and without significant artifacts.
KEY POINTS: Question Can diffusion-weighted imaging (DWI) be incorporated into clinical 1.5-T and 3-T breast MRI protocols without adding acquisition time? Findings The signal characteristics and conspicuity of breast lesions on low b-value (b0) DWI were not inferior compared with that on standard T2-weighted/fluid-sensitive imaging. Clinical relevance The incorporation of low b-value DWI can translate to improved cost-effectiveness and patient experience of breast MRI by reducing false-positives and reducing overall scan time.