Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics · 2026
[Association between a low bone mass and prefrailty in community-dwelling older women and their physical, psychological, and cognitive functions].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Katsurasako Tsuyoshi, Kikuchi Yuki, Nakano Hideki, Goda Akio, Mori Kohei, Shiraiwa Kayoko, Horie Jun, Murata Shin
Аннотация
AIM: The combination of frailty and osteoporosis increases the fracture risk more than either condition alone. Therefore, it is necessary to clarify the characteristics of older adults with a combination of pre-frailty, a precursor to frailty, and a low bone mass and to consider appropriate preventive interventions. This study aimed to clarify the characteristics of older women with combined pre-frailty and a reduced bone mass, a precursor to frailty, and to obtain findings that contribute to both early detection and screening.
METHODS: A total of 292 community-dwelling women aged ≥ 65 years were classified into four groups based on the presence or absence of a low bone mass and prefrailty: a normal, low bone mass, prefrail, and a low bone mass with prefrail groups. The physical, psychological, and cognitive functions were compared between the groups. A multinomial logistic regression analysis was conducted to identify the associated factors.
RESULTS: The proportions in each group were 29.8% in the normal group, 27.7% in the low bone mass group, 18.5% in the pre-frail group, and 24.0% in the low bone mass and pre-frail group. In the prefrail group, the Geriatric Depression Scale-5 (GDS-5; odds ratio [OR]= 2.536, 95% confidence interval [CI]: 1.586-4.057) and a fear of falling (OR=2.662, 95%CI: 1.227-5.779) emerged as significant associated factors. In the low bone mass with prefrailty group, significant factors included TUG (OR=1.979, 95%CI: 1.188-3.296), MMSE (OR=0.771, 95%CI: 0.633-0.940), GDS-5 (OR=2.775, 95%CI: 1.732-4.368), and a fear of falling (OR=2.303, 95%CI: 1.091-4.860). However, no significant associated factors were identified in the low bone mass group.
CONCLUSIONS: The combination of a reduced bone mass and pre-frailty resulted in a more multifaceted functional decline than either condition alone. These findings suggest the usefulness of screening for a reduced bone mass and frailty in community-dwelling older women.
METHODS: A total of 292 community-dwelling women aged ≥ 65 years were classified into four groups based on the presence or absence of a low bone mass and prefrailty: a normal, low bone mass, prefrail, and a low bone mass with prefrail groups. The physical, psychological, and cognitive functions were compared between the groups. A multinomial logistic regression analysis was conducted to identify the associated factors.
RESULTS: The proportions in each group were 29.8% in the normal group, 27.7% in the low bone mass group, 18.5% in the pre-frail group, and 24.0% in the low bone mass and pre-frail group. In the prefrail group, the Geriatric Depression Scale-5 (GDS-5; odds ratio [OR]= 2.536, 95% confidence interval [CI]: 1.586-4.057) and a fear of falling (OR=2.662, 95%CI: 1.227-5.779) emerged as significant associated factors. In the low bone mass with prefrailty group, significant factors included TUG (OR=1.979, 95%CI: 1.188-3.296), MMSE (OR=0.771, 95%CI: 0.633-0.940), GDS-5 (OR=2.775, 95%CI: 1.732-4.368), and a fear of falling (OR=2.303, 95%CI: 1.091-4.860). However, no significant associated factors were identified in the low bone mass group.
CONCLUSIONS: The combination of a reduced bone mass and pre-frailty resulted in a more multifaceted functional decline than either condition alone. These findings suggest the usefulness of screening for a reduced bone mass and frailty in community-dwelling older women.