International journal of dermatology · 2005
Investigation of herpes simplex virus DNA in pityriasis rosea by polymerase chain reaction.
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Bozdag Kübra Eren, Güven Füsun Ozder, Zeytinoglu Aysin, Erensoy Selda, Karaman Ahmet, Bilgiç Altýnay
Аннотация
BACKGROUND: Pityriasis rosea (PR) is an acute, inflammatory disease of unknown cause. Clinical and experimental findings indicate an infectious etiology of PR. Our purpose is to examine the skin lesions and blood samples of PR patients by polymerase chain reaction (PCR) for the presence of HSV type 1 and 2 DNA.
METHODS: The lesional skin biopsies from 10 patients and blood samples from two randomized patients with clinically and histologically confirmed pityriasis rosea were examined by PCR.
RESULTS: No HSV 1 and HSV 2 DNA was detected in the lesional biopsy and blood samples.
CONCLUSIONS: We could not identify a relationship between HSV 1, HSV 2 and PR.
METHODS: The lesional skin biopsies from 10 patients and blood samples from two randomized patients with clinically and histologically confirmed pityriasis rosea were examined by PCR.
RESULTS: No HSV 1 and HSV 2 DNA was detected in the lesional biopsy and blood samples.
CONCLUSIONS: We could not identify a relationship between HSV 1, HSV 2 and PR.