Serum amyloid A (SAA) as a biomarker of chronic infection due to boat strike trauma in a free-ranging Florida manatee (Trichechus manatus latirostris) with incidental polycystic kidneys.

BACKGROUND AND PURPOSE: Middle ear prostheses are among the smallest implanted medical devices, with diameters as small as 0.25 mm. Accurate postoperative imaging is critical for assessing prosthesis placement, detecting complications such as dislodgement or extrusion, and informing potential revisions. Conventional energy-integrating detector CT (EID-CT) is traditionally used for imaging these implants; however, with the recent clinical use of photon-counting detector CT (PCD-CT), further analysis on multiple parameters is required to assess future utility. This study compares the spatial resolution and visualization quality of middle ear prostheses between EID-CT and PCD-CT. We hypothesize that PCD-CT will provide superior spatial resolution of prostheses, allowing for more accurate postoperative assessments to facilitate improved clinical decision-making.

MATERIALS AND METHODS: This retrospective study included 10 patients with various middle ear prostheses, including total ossicular replacement prostheses, partial ossicular replacement prostheses (PORP), stapes prostheses, and the middle ear portion of cochlear implants. Each patient underwent temporal bone imaging on both EID-CT and PCD-CT scanners using institutional high-resolution protocols. A total of 30 line profiles were analyzed, with peak intensity (HU) and full width at half maximum (FWHM) calculated from the intensity curves along the prosthetic shafts. Paired t tests were used to assess differences in image-quality metrics between PCD-CT and EID-CT.

RESULTS: PCD-CT demonstrated significantly higher mean peak intensity values (4855.8 [SD, 3944.3] HU ) compared with EID-CT (2498.7 [SD, 2135.9] HU), with a mean difference of 2357 HU (95% CI, 77-4638; HU; P = .04). Spatial resolution, measured as FWHM, was significantly better with PCD-CT (mean, 0.4 [SD, 0.2]) than EID-CT (mean, 0.6 [SD, 0.3] mm), with a mean difference of -0.2 mm (95% CI, -0.3 to -0.1; P = .002).

CONCLUSIONS: PCD-CT demonstrates advantages in spatial resolution and image quality over conventional EID-CT for postoperative evaluation of middle ear prostheses. Enhanced visualization may improve diagnostic confidence and enable more accurate postoperative assessment and complication detection.