[Complex radionuclide diagnosis of tumor lesions of the bones].

A complex examination of 320 patients with breast tumors of varying degree of advancement was carried out. Also, the data on examination of 20 cases of fibrous-cystic mastopathy and 40 healthy females were analysed. Similar studies were conducted in 20 cases of acute and chronic osteomyelitis, 14--tuberculosis of bones and joints, 63--rheumatoid arthritis and 36--Bekhterev's disease. Pyrphotech, Tc99m; pyrophosphate, Tc99m and diphosphonate Tc99m were used in carrying out scintigraphic examination. Parathyrin, prolactin, carcinoembryonic antigen (CEA), alpha-fetoprotein and ferritin were assayed in patients' blood serum. Tumor dissemination to bones was matched by a significant rise in CEA and prolactin levels. However, these parameters were normal in patients with non-tumor skeletal pathology. No significant rise in ferritin and alpha-fetoprotein were recorded in all patients. The specificity of the said complex examination, including osteoscintigraphy and blood plasma parathyrin assays in breast cancer patients, was 79%.