Eye (London, England) · 2026
OphthoEvidence: a model for rapid and trustworthy ophthalmology guidelines.
СтатьяНазвание и аннотация: Перевод в очереди
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Lima João Pedro, Zeraatkar Dena, Al Masri Marah, Sivaprasad Sobha, Steel David H, Wong Tien Yin, Wykoff Charlie C, Chaudhary Varun
Аннотация
INTRODUCTION: The World Health Organization estimates that 2.2 billion people worldwide suffer from vision impairment, representing an annual productivity loss of US$411 billion. Meanwhile, ophthalmology advances at a fast-moving pace. As in every discipline, optimal ophthalmologic care depends on trustworthy clinical practice guidelines that promote patient-centred care and support consistent, evidence-informed decision-making. Existing guidelines, however, may not always be up to date and their adherence to internationally accepted standards for trustworthy development is variable.
METHODS: We describe OphthoEvidence, a model for producing rigorous clinical practice guidelines supported by systematic reviews and aligned with international trustworthy standards. Panels (8-14 stakeholders) including clinicians, patients, caregivers, researchers, and health-system decision makers will use the GRADE Evidence-to-Decision framework to formulate recommendations. A parallel Evidence Synthesis Team will conduct systematic reviews that will help panel members move from evidence to final recommendations.
CONCLUSION: OphthoEvidence will serve as an implementation model for the development of clinical practice guidelines in ophthalmology, adhering to international standards that ensure trustworthiness, transparency, and reproducibility while proposing a framework for other research groups and regulatory bodies.
METHODS: We describe OphthoEvidence, a model for producing rigorous clinical practice guidelines supported by systematic reviews and aligned with international trustworthy standards. Panels (8-14 stakeholders) including clinicians, patients, caregivers, researchers, and health-system decision makers will use the GRADE Evidence-to-Decision framework to formulate recommendations. A parallel Evidence Synthesis Team will conduct systematic reviews that will help panel members move from evidence to final recommendations.
CONCLUSION: OphthoEvidence will serve as an implementation model for the development of clinical practice guidelines in ophthalmology, adhering to international standards that ensure trustworthiness, transparency, and reproducibility while proposing a framework for other research groups and regulatory bodies.