Biliary Atresia: A Focus on the Patient Journey from Diagnosis to Transplant.

Biliary atresia is a complex cholangiopathy of infancy characterized by extrahepatic biliary obstruction and progressive intrahepatic fibroinflammatory injury. It remains the leading indication for liver transplant in children without any disease-modifying medical therapies. Herein the authors review updated literature relevant to the patient journey from diagnosis through end-stage liver disease up to liver transplantation. They focus on the burden of disease throughout this course including a focus on actionable areas of potential future study that could help transform patient care.