Burns : journal of the International Society for Burn Injuries · 2026
Analysis of the efficacy of intense pulsed light combined with collagen wound dressings for treating facial postburn hyperpigmentation.
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
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Chen Yuanyuan, Guo Yan, Sun Haoyuan, Liu Tong, Tang Yuting, Wang Jianjun, Liu Jinyi, He Qian, Qin Chunli, Shen Jiangyong
Аннотация
BACKGROUND: Various treatments are available for postburn hyperpigmentation; however, the results are often disappointing.
OBJECTIVE: To evaluate the clinical efficacy and therapeutic value of intense pulsed light (IPL) combined with collagen wound dressings to treat facial postburn hyperpigmentation.
METHODS: Ninety patients with facial hyperpigmentation from second-degree burns were randomized to receive IPL plus collagen dressings or collagen dressings alone for 3 months. Evaluations were conducted using visual assessments, VISIA skin analysis, imaging software, and psychological scales.
RESULTS: Of the 90 patients, 80 completed the study. The efficacy rate was 95.1 % in the experimental group versus 61.5 % in the control group (p < 0.05). Quantitative image analysis showed a significantly greater reduction in both the area and intensity (Average Optical Density) of hyperpigmentation in the experimental group compared to the control (p < 0.05). VISIA skin analysis confirmed superior improvement in spots, UV spots, and brown spots in the combination therapy group (p < 0.05). Furthermore, patients receiving combination therapy reported significantly greater satisfaction and showed more pronounced improvements in anxiety and depression scores (SAS and SDS, p < 0.05) than the control group.
CONCLUSION: IPL combined with collagen wound dressings is effective and safe for treating facial postburn hyperpigmentation with minimal side effects. This treatment can also improve patients' psychological well-being and is recommended for clinical use.
OBJECTIVE: To evaluate the clinical efficacy and therapeutic value of intense pulsed light (IPL) combined with collagen wound dressings to treat facial postburn hyperpigmentation.
METHODS: Ninety patients with facial hyperpigmentation from second-degree burns were randomized to receive IPL plus collagen dressings or collagen dressings alone for 3 months. Evaluations were conducted using visual assessments, VISIA skin analysis, imaging software, and psychological scales.
RESULTS: Of the 90 patients, 80 completed the study. The efficacy rate was 95.1 % in the experimental group versus 61.5 % in the control group (p < 0.05). Quantitative image analysis showed a significantly greater reduction in both the area and intensity (Average Optical Density) of hyperpigmentation in the experimental group compared to the control (p < 0.05). VISIA skin analysis confirmed superior improvement in spots, UV spots, and brown spots in the combination therapy group (p < 0.05). Furthermore, patients receiving combination therapy reported significantly greater satisfaction and showed more pronounced improvements in anxiety and depression scores (SAS and SDS, p < 0.05) than the control group.
CONCLUSION: IPL combined with collagen wound dressings is effective and safe for treating facial postburn hyperpigmentation with minimal side effects. This treatment can also improve patients' psychological well-being and is recommended for clinical use.