The use of cleansers as therapeutic concomitants in various dermatologic disorders.

The choice of a mild cleansing agent is important in the adjunctive management of various skin conditions, such as atopic dermatitis, acne vulgaris, rosacea, photoaging, retinoid-induced irritant dermatitis, and sensitive skin. There are 3 major categories of cleansing agents: soaps, synthetic detergents, and lipid-free cleansing agents. The irritancy potential of cleansing agents is a function of a number of factors, including the pH, type of surfactants, and amount of skin residue. Furthermore, the presence of humectants and emollients also can influence the overall mildness of a cleansing agent. Agents with slightly acidic or neutral pH, nonionic surfactants, and minimal skin residue may be preferable for people who are at increased risk for irritancy reactions.