Indian pediatrics · 2026
In-Hospital Outcomes of Very Preterm and Very Low Birth Weight Neonates: A Multicenter Retrospective Study from India.
СтатьяМногоцентровое исследованиеНазвание и аннотация: Перевод в очереди
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Vardhelli Venkateshwarlu, Vadije Praveen Rao, Kishore Kumar Rajagopal, Venkatesh Vidheya, Kasaragod Arvind Balakrishna
Аннотация
OBJECTIVE: To determine the in-hospital neonatal outcomes of very preterm and very low birth weight (VLBW) neonates delivered in tertiary neonatal centres in India.
METHODS: This retrospective study analyzed the in-hospital outcomes of very preterm (240/7-316/7) and VLBW (501-1500 g) born between January 2018 and December 2022 from 14 tertiary neonatal units across India. Survival during hospital stay and morbidities, including bronchopulmonary dysplasia (BPD) at 36 weeks post-menstrual age, intraventricular hemorrhage (IVH), periventricular leukomalacia (PVL), and retinopathy of prematurity (ROP), were analyzed.
RESULTS: A total of 1691 very preterm neonates with a mean (SD) gestational age of 29 (1.9) weeks were included. Survival on discharge rates were 8.7% at 24 weeks, 51% at 25 weeks, 67.2% at 26 weeks, 86.3% at 27 weeks, 89.8% at 28 weeks, 92.2% at 29 weeks, 93.5% at 30 weeks, 97.7% at 31 weeks. 87.8% very preterm neonates were alive on discharge; corresponding figures for extreme preterm and extremely low birth weight (ELBW) neonates were 64.4% and 66.3%, respectively. Morbidity rates were 4% (n = 67) for BPD, 2.4% (n = 40) for IVH grade 3 or more, 0.9% (n = 15) for cystic PVL, and 5.1% (n = 86) for ROP requiring treatment. The VLBW group included 1,754 neonates with a mean (SD) gestational age of 29.8 (2.8) weeks. Survival before discharge in the VLBW group was 88%.
CONCLUSION: The survival and outcomes of very preterm and VLBW neonates from these tertiary neonatal centers in India were good.
METHODS: This retrospective study analyzed the in-hospital outcomes of very preterm (240/7-316/7) and VLBW (501-1500 g) born between January 2018 and December 2022 from 14 tertiary neonatal units across India. Survival during hospital stay and morbidities, including bronchopulmonary dysplasia (BPD) at 36 weeks post-menstrual age, intraventricular hemorrhage (IVH), periventricular leukomalacia (PVL), and retinopathy of prematurity (ROP), were analyzed.
RESULTS: A total of 1691 very preterm neonates with a mean (SD) gestational age of 29 (1.9) weeks were included. Survival on discharge rates were 8.7% at 24 weeks, 51% at 25 weeks, 67.2% at 26 weeks, 86.3% at 27 weeks, 89.8% at 28 weeks, 92.2% at 29 weeks, 93.5% at 30 weeks, 97.7% at 31 weeks. 87.8% very preterm neonates were alive on discharge; corresponding figures for extreme preterm and extremely low birth weight (ELBW) neonates were 64.4% and 66.3%, respectively. Morbidity rates were 4% (n = 67) for BPD, 2.4% (n = 40) for IVH grade 3 or more, 0.9% (n = 15) for cystic PVL, and 5.1% (n = 86) for ROP requiring treatment. The VLBW group included 1,754 neonates with a mean (SD) gestational age of 29.8 (2.8) weeks. Survival before discharge in the VLBW group was 88%.
CONCLUSION: The survival and outcomes of very preterm and VLBW neonates from these tertiary neonatal centers in India were good.