Definitive Surgical Management of Refractory Amiodarone-Induced Thyrotoxicosis in a Cardiac Patient: A Case Report.

Amiodarone-induced thyrotoxicosis (AIT) presents a significant therapeutic challenge, particularly in patients with underlying cardiac comorbidities. We present a 58-year-old man with a background history of ischemic heart disease and atrial fibrillation who developed AIT following long-term amiodarone use. Despite the escalation of medical therapy, he remained clinically and biochemically thyrotoxic with symptomatic atrial fibrillation. Definitive management via total thyroidectomy was performed, resulting in clinical stabilization. This case highlights the importance of early multidisciplinary input and the role of total thyroidectomy in managing refractory AIT in high-risk cardiac patients.