Rare complication of ventricular septal defect in three patients following transcatheter aortic valve replacement.

Transcatheter aortic valve replacement (TAVR) is a highly-effective but technically challenging procedure. Despite improvement in device technology and operator techniques, complications are common and previously unknown procedural-related complications continue to arise. In this report, we present a case series of three patients with acquired perimembranous ventricular septal defects following transfemoral TAVR with an Edwards SAPIEN prosthesis.