The International journal of neuroscience · 2026
The effects of robot-assisted physiotherapy on motor and cognitive recovery in individuals with hemiparetic stroke: a pilot randomized controlled trial.
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Çekok Fatma Kübra, Gökşen Ayşenur, Bellur Nurel, Mutlu Ali
Аннотация
AIM: Stroke often leads to persistent motor and cognitive impairments, which can significantly limit functional independence. This study aimed to investigate the effects of a robot-assisted physiotherapy program on motor and cognitive outcomes in individuals with hemiparetic stroke.
METHODS: Twenty individuals with hemiparetic stroke were randomly assigned to an experimental group (EG, n = 10), receiving robot-assisted physiotherapy (THERA-Trainer-based training) combined with Bobath exercises, or a control group (CG, n = 10), receiving patient-specific Bobath exercises alone. The Mini-Mental State Examination (MMSE) was administered at baseline to assess cognitive status. Outcome measures included the Digit Span Forward (DSF), Digit Span Backward (DSB), Frenchay Arm Test, Fugl-Meyer Assessment-Upper Extremity (FMA-UE), Fugl-Meyer Assessment-Lower Extremity (FMA-LE), Mini-Balance Evaluation Systems Test (Mini-BESTest), Timed Up and Go (TUG), Timed Up and Go Cognitive (TUG-C), and Five Times Sit-to-Stand (5STS). Oxygen saturation (SpO2) and heart rate (HR) were monitored at baseline, at the end of the 5STS, and 1 min after the test.
RESULTS: The EG demonstrated significantly greater improvements in both cognitive performance and upper and lower limb motor function compared to the CG (p < 0.05). In addition, the EG showed superior improvements in TUG (p = 0.001) and TUG-C (p < 0.001), enhanced post-test SpO2 recovery (p = 0.011), and reduced baseline HR (p = 0.001).
CONCLUSION: These findings suggest that integrating robot-assisted physiotherapy into standard rehabilitation may provide clinically meaningful benefits in individuals with subacute stroke. The combined approach appears to enhance both motor and cognitive recovery, supporting improved functional independence.
METHODS: Twenty individuals with hemiparetic stroke were randomly assigned to an experimental group (EG, n = 10), receiving robot-assisted physiotherapy (THERA-Trainer-based training) combined with Bobath exercises, or a control group (CG, n = 10), receiving patient-specific Bobath exercises alone. The Mini-Mental State Examination (MMSE) was administered at baseline to assess cognitive status. Outcome measures included the Digit Span Forward (DSF), Digit Span Backward (DSB), Frenchay Arm Test, Fugl-Meyer Assessment-Upper Extremity (FMA-UE), Fugl-Meyer Assessment-Lower Extremity (FMA-LE), Mini-Balance Evaluation Systems Test (Mini-BESTest), Timed Up and Go (TUG), Timed Up and Go Cognitive (TUG-C), and Five Times Sit-to-Stand (5STS). Oxygen saturation (SpO2) and heart rate (HR) were monitored at baseline, at the end of the 5STS, and 1 min after the test.
RESULTS: The EG demonstrated significantly greater improvements in both cognitive performance and upper and lower limb motor function compared to the CG (p < 0.05). In addition, the EG showed superior improvements in TUG (p = 0.001) and TUG-C (p < 0.001), enhanced post-test SpO2 recovery (p = 0.011), and reduced baseline HR (p = 0.001).
CONCLUSION: These findings suggest that integrating robot-assisted physiotherapy into standard rehabilitation may provide clinically meaningful benefits in individuals with subacute stroke. The combined approach appears to enhance both motor and cognitive recovery, supporting improved functional independence.