Annals of hematology · 2025
A fatal case of peritonitis due to colonic localization of acute myeloid leukemia.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Buzzatti Elisa, Botti Caterina, Presicci Roberta, Mauro Cristina, Blasi Francesca, Paterno Giovangiacinto, Savino Luca, Palmieri Raffaele, Gurnari Carmelo, Ottone Tiziana, Mallegni Flavia, Meddi Elisa, Moretti Federico, Tiravanti Ilaria, Cardillo Lucia, Mezzanotte Valeria, Taka Kristian, De Marchi Lucrezia, Venditti Adriano, Villa Massimo, Del Principe Maria Ilaria
Аннотация
Myeloid sarcoma (MS) is an extramedullary localization of immature granulocyte cells that can occur in association with acute myeloid leukemia (AML). Gastrointestinal involvement is relatively common in MS, but exclusive colonic localization is a rare occurrence. Here, we report on a 53-year-old male patient affected by AML developing a severe abdominal pain caused by intestinal perforation requiring surgical intervention. The post-mortem examination revealed an infiltrate consistent with MS. Diagnosis of colonic MS can be difficult due to non-specific symptoms and complicated by the challenges associated with exploring this area. Clinical acumen is crucial to promptly establish adequate management due to the potentially life-threatening nature of this condition.