The Journal of veterinary medical science · 2009
Hypophysectomy for a dog with coexisting Cushing's disease and diabetes mellitus.
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Ishino Hirokazu, Hara Yasushi, Teshima Takahiro, Tanaka Shigeki, Takekoshi Susumu, Nezu Yoshinori, Harada Yasuji, Yogo Takuya, Sako Toshinori, Koyama Hidekazu, Teramoto Akira, Osamura Robert Y, Tagawa Masahiro
Аннотация
An 11-year-old male mixed breed dog diagnosed with Cushing's disease and diabetes mellitus was treated by hypophysectomy. After surgery, the hypercortisolemia disappeared and the diabetes status improved. The insulin requirement to control hyperglycemia gradually decreased. At 12 weeks after surgery, there was no requirement for insulin and we suspected the diabetes was completely resolved. In the present case, diabetes mellitus seems to be secondary to Cushing's disease. In conclusion, this mixed breed dog with coexisting Cushing's disease and diabetes mellitus is the first case showing the effectiveness of hypophysectomy to treat diabetes mellitus secondary to Cushing's disease in dogs.