Voprosy pitaniia · 2025
[Clinical case of association of food and pollen allergy with acne].
СтатьяКлинический случайАннотация на английскомНазвание и аннотация: Перевод в очереди
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Barilo A A, Smirnova S V
Аннотация
UNLABELLED: Acne is a chronic inflammatory disease of the sebaceous glands characterized by excessive sebum production, follicular hyperkeratinization, and skin inflammation. The relevance of this study stems from the need for acne patients to receive dietary recommendations when consulting dermatologists. Data on the influence of food allergies on acne development are extremely limited, making this study particularly relevant. The aim of the study was to present a clinical case of association of food allergy with acne and concomitant hay fever in a patient.
MATERIAL AND METHODS: A specific allergological examination was performed on a 15-year-old patient who had been diagnosed with acne for 3 years. The determination of the level of total immunoglobulin E (IgE), eosinophilic cationic protein in the blood serum by the method of solid-phase enzyme immunoassay, skin prick testing with food and pollen allergens were carried out.
RESULTS: Increased serum levels of total IgE (284 IU/ml, reference values: 0-100 IU/ml) and eosinophil cationic protein (36 ng/ml, reference values: 0-24 ng/ml) were detected. Skin prick testing revealed a hyperergic reaction (25 mm) to tree pollen, a positive reaction (6-10 mm) to wheat flour and oatmeal proteins, milk protein, cereal pollen, and apples, and a weakly positive reaction (3-5 mm) to tomatoes and rye flour protein. After 2 months, a positive clinical effect was noted as a result of elimination diet prescribed taking into account the causative and cross-reactive allergens (including common antigenic determinants) with the exclusion of dairy products, rolled oats, bran, oatmeal cookies, cereal porridges, pasta, peanuts, all types of smoked sausages, coffee, cocoa, ice cream, sherbet, sesame, sorghum, honey and bee products, strawberries, citrus fruits, soy, sorrel, herbal teas, tree fruits (raw apples, peaches, cherries), as well as nuts, celery, raw carrots, tomatoes, exotic fruits.
CONCLUSION: The presented case demonstrates the need for a specific allergological examination of patients with acne with concomitant sensitization to pollen allergens in case of resistance to standard therapy in order to select a personalized elimination diet with the exclusion of causative and cross-reactive allergens.
MATERIAL AND METHODS: A specific allergological examination was performed on a 15-year-old patient who had been diagnosed with acne for 3 years. The determination of the level of total immunoglobulin E (IgE), eosinophilic cationic protein in the blood serum by the method of solid-phase enzyme immunoassay, skin prick testing with food and pollen allergens were carried out.
RESULTS: Increased serum levels of total IgE (284 IU/ml, reference values: 0-100 IU/ml) and eosinophil cationic protein (36 ng/ml, reference values: 0-24 ng/ml) were detected. Skin prick testing revealed a hyperergic reaction (25 mm) to tree pollen, a positive reaction (6-10 mm) to wheat flour and oatmeal proteins, milk protein, cereal pollen, and apples, and a weakly positive reaction (3-5 mm) to tomatoes and rye flour protein. After 2 months, a positive clinical effect was noted as a result of elimination diet prescribed taking into account the causative and cross-reactive allergens (including common antigenic determinants) with the exclusion of dairy products, rolled oats, bran, oatmeal cookies, cereal porridges, pasta, peanuts, all types of smoked sausages, coffee, cocoa, ice cream, sherbet, sesame, sorghum, honey and bee products, strawberries, citrus fruits, soy, sorrel, herbal teas, tree fruits (raw apples, peaches, cherries), as well as nuts, celery, raw carrots, tomatoes, exotic fruits.
CONCLUSION: The presented case demonstrates the need for a specific allergological examination of patients with acne with concomitant sensitization to pollen allergens in case of resistance to standard therapy in order to select a personalized elimination diet with the exclusion of causative and cross-reactive allergens.