A case report of bullous pemphigoid following secukinumab therapy for a patient with psoriasis.

Aim: Bullous pemphigoid induced by secukinumab in treatment of psoriasis is rare.

Methods

We report a 49-year-old man with psoriasis who developed bullous pemphigoid during treatment with secukinumab.

Results

Scattered tense vesicles with itching appeared all over the body after the fourth treatment. Bullous pemphigoid was confirmed by pathological examination and direct immunofluorescence. The patient was treated with topical corticosteroids, oral nicotinamide and minocycline hydrochloride. The lesions of bullous pemphigoid improved significantly after 7 days of treatment.

Conclusions

Bullous pemphigoid is a rare adverse event following administration of secukinumab.