Journal of health economics and outcomes research · 2019
Healthcare Utilization, Costs of Care, and Mortality Among Patients With Spinal Muscular Atrophy.
СтатьяНазвание и аннотация: Перевод в очереди
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Tan Hiangkiat, Gu Tao, Chen Er, Punekar Rajeshwari, Shieh Perry B
Аннотация
OBJECTIVES: To understand treatment patterns, healthcare resource utilization, and costs of care among patients with spinal muscular atrophy (SMA). Methods: SMA patients were identified from a large managed care population using administrative claims data from January 2006 to March 2016. Patients were classified into infantile, childhood-onset, and late-onset groups based on age of first SMA diagnosis. They were matched 1:1 to non-SMA patients based on age, gender, geography, and health plan type.
RESULTS: In the infantile group, 17.4% and 26.1% were treated with invasive and non-invasive ventilation, respectively. Uses of orthotics/orthoses and orthopedic surgery were frequent: 54.5% and 22.7% childhood group; 27.0% and 38.5% late-onset group. Mean per member per month costs in SMA vs. matched non-SMA patients was $25,517 vs. $406 (infantile); $6,357 vs. $188 (childhood-onset); $2,499 vs. $742 (late-onset).
CONCLUSIONS: SMA patients, particularly with infantile onset, incurred significantly higher healthcare utilization and costs than the general population.
RESULTS: In the infantile group, 17.4% and 26.1% were treated with invasive and non-invasive ventilation, respectively. Uses of orthotics/orthoses and orthopedic surgery were frequent: 54.5% and 22.7% childhood group; 27.0% and 38.5% late-onset group. Mean per member per month costs in SMA vs. matched non-SMA patients was $25,517 vs. $406 (infantile); $6,357 vs. $188 (childhood-onset); $2,499 vs. $742 (late-onset).
CONCLUSIONS: SMA patients, particularly with infantile onset, incurred significantly higher healthcare utilization and costs than the general population.