Turkish archives of otorhinolaryngology · 2025
Investigation of Serum Calcium and Vitamin D Levels in Patients with Refractory Benign Paroxysmal Positional Vertigo.
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Bayrak Asuman Feda, Çetin Baturalp, Doğan Mehmet
Аннотация
OBJECTIVE: It is not known exactly what causes recurrence in benign paroxysmal positional vertigo (BPPV) patients. We aimed to investigate the relationship between the number of maneuvers and serum vitamin D and calcium levels in BPPV cases treated with appropriate maneuvers after correct diagnosis.
METHODS: A total of 86 BPPV patients, 68 (79.9%) female and 18 (20.1%) male were included in the study. Of these, 16.3% (n=14) were aged under 45 years, 29.1% (n=25) between 45-60 years, and 54.7% (n=47) over 60 years. All were evaluated with videonystagmography. Patients who underwent maneuvers for BPPV treatment were examined. Serum 25-hydroxyvitamin D and calcium levels were measured.
RESULTS: Repeated maneuvers were performed in 43% of the patients (n=37). Serum calcium measurements did not differ significantly between the groups. Serum vitamin D levels were not significantly different between the groups in terms of sex (p=0.387) and age (p=0.323). However, vitamin D levels were significantly lower in the group that resisted the maneuvers than in the group that did not resist [resistance: 22.9, interquartile range (IQR): 12.9-27.0; non-resistance: 28.6, IQR: 18-35, p=0.009].
CONCLUSION: Vitamin D measurements were observed to be significantly lower in patients requiring repeat maneuvers for BPPV treatment. We recommend that vitamin D levels be evaluated in resistant cases.
METHODS: A total of 86 BPPV patients, 68 (79.9%) female and 18 (20.1%) male were included in the study. Of these, 16.3% (n=14) were aged under 45 years, 29.1% (n=25) between 45-60 years, and 54.7% (n=47) over 60 years. All were evaluated with videonystagmography. Patients who underwent maneuvers for BPPV treatment were examined. Serum 25-hydroxyvitamin D and calcium levels were measured.
RESULTS: Repeated maneuvers were performed in 43% of the patients (n=37). Serum calcium measurements did not differ significantly between the groups. Serum vitamin D levels were not significantly different between the groups in terms of sex (p=0.387) and age (p=0.323). However, vitamin D levels were significantly lower in the group that resisted the maneuvers than in the group that did not resist [resistance: 22.9, interquartile range (IQR): 12.9-27.0; non-resistance: 28.6, IQR: 18-35, p=0.009].
CONCLUSION: Vitamin D measurements were observed to be significantly lower in patients requiring repeat maneuvers for BPPV treatment. We recommend that vitamin D levels be evaluated in resistant cases.