Revista espanola de enfermedades digestivas · 2021
Outcomes of drug-induced acute pancreatitis: a ten-year experience of an academic center.
СтатьяНазвание и аннотация: Перевод в очереди
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Sánchez-Aldehuelo Rubén, García García de Paredes Ana, Rojo Lázaro Diego, Martínez Ortega Antonio, García de la Filia Molina Irene, López-Durán Sergio, Rodríguez-Gandía Miguel Ángel, López-Sanromán Antonio, Albillos Agustín
Аннотация
BACKGROUND: drug-induced pancreatitis is an unexplored entity.
METHODS: a retrospective cohort study was performed at a referral center. Patients with drug-induced acute pancreatitis between 2008 and 2018 were included. Baseline patient characteristics, involved drugs, clinical course and recurrence were analyzed.
RESULTS: drug-induced pancreatitis represented 2.8 % of acute pancreatitis (47/1,665) and 18 different drugs were involved (thiopurines 61.8 %). The latency period was less than one month in 87.2 % of cases. Pancreatitis was mild in 89.3 % and recurrence risk was 2.3 %.
CONCLUSION: drugs are a rare cause of pancreatitis, which mostly occurs within the first month of treatment, is usually mild and is associated with a low risk of recurrence.
METHODS: a retrospective cohort study was performed at a referral center. Patients with drug-induced acute pancreatitis between 2008 and 2018 were included. Baseline patient characteristics, involved drugs, clinical course and recurrence were analyzed.
RESULTS: drug-induced pancreatitis represented 2.8 % of acute pancreatitis (47/1,665) and 18 different drugs were involved (thiopurines 61.8 %). The latency period was less than one month in 87.2 % of cases. Pancreatitis was mild in 89.3 % and recurrence risk was 2.3 %.
CONCLUSION: drugs are a rare cause of pancreatitis, which mostly occurs within the first month of treatment, is usually mild and is associated with a low risk of recurrence.