From Aesthetic to Alarming: Ductal Carcinoma In Situ Following Breast Fat Grafting.

This case presents a rare occurrence of ductal carcinoma in situ (DCIS) in a patient with a history of bilateral iatrogenic fat injections, aiming to contribute to the ongoing discussion on potential associations between fat grafting and breast pathology. A 43-year-old Saudi woman presented with bilateral palpable masses at the sites of previous fat grafting performed two years earlier. Despite having no significant risk factors or family history of breast cancer, imaging revealed a suspicious asymmetry adjacent to the palpable area in the left breast. Biopsy of this region confirmed fat necrosis with foci of atypical ductal hyperplasia and low-grade DCIS. This case underscores the importance of vigilant follow-up in patients undergoing autologous fat grafting to the breast.