Transplant infectious disease : an official journal of the Transplantation Society · 2011
Recurrent leishmaniasis in kidney transplant recipients: report of 2 cases and systematic review of the literature.
Клинический случайСтатьяСистематический обзорНазвание и аннотация: Перевод в очереди
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Simon I, Wissing K M, Del Marmol V, Antinori S, Remmelink M, Nilufer Broeders E, Nortier J L, Corbellino M, Abramowicz D, Cascio A
Аннотация
The characteristics of 8 episodes of leishmaniasis with atypical manifestations in 2 Italian kidney transplant recipients are analyzed and contextualized among those of 52 other episodes of leishmaniasis observed in 19 transplant recipients found through a systematic review of the international literature. In all the patients, the initial episode was visceral leishmaniasis, which was associated with mucocutaneous involvement in 2 cases. With the exception of 1 case of post kala-azar dermal leishmaniasis, 2 episodes of Leishmania endophthalmitis, and 3 episodes of mucocutaneous leishmaniasis, all the recurrences were characterized by visceral involvement. The potential role of polymerase chain reaction in monitoring the infection, the importance of a long follow-up, the potential benefit of chemoprophylaxis, and the therapeutic challenges are discussed.