Magnetic Resonance-Guided Focused Ultrasound Treatment for Essential Tremor: A Single-Center Experience.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Hvingelby Victor S, Kjeldsen Pernille, Bergholt Bo, Schechtmann Gaston Andres, Danielsen Erik Hvid, Møller Mette, Johnsen Erik Lisbjerg, Mardosiene Skirmante, Lund Torben Ellegaard, Grauballe Dora, Geneser Michael, Sørensen Tina Vincens, Bak Lisa Østergaard, Andreasen Martin, Andersen Anne Sofie Møller, Andersen Lone, Meier Kaare, Juhl Niels, Tankisi Alp, Jespersen Bo, Eriksen Christian Fenger, Rasmussen Mads, Eriksen Winnie Bechmann, Barrutia Birgitte, Kromann Mette, Baandrup Ida, Bjørn Jette, Stjernholm Rie, Bræmer-Madsen Charlotte, Jørgensen Signe Mygdal, Sørensen Jens Christian Hedemann, Glud Andreas Nørgaard
Аннотация
OBJECTIVE: The aim was to obtain the results of the first 108 patients treated with MRgFUS in Denmark.
METHODS: Data were entered in a quality assurance database at baseline and 3, 6, and 12 months. Clinician- and patient-rated treatment efficacy was evaluated using the Fahn-Marin-Tolosa (FMT) scale and the Patient Global Impression of Change.
RESULTS: A total of 108 persons have currently been treated. Tremor improved by a total mean 6.39 points (95% confidence interval [CI]: 5.01;7.76, P < 0.00001) and 9.63 points (95% CI: 7.60;11.66, P < 0.00001), 10.42 (95% CI: 9.06;11.79, P < 0.00001), and 26.45 (95% CI: 22.46;30.43, P < 0.00001) for FMT parts A, B, and C, respectively, at 3 months. Side effects occurred in 65.7% of patients at 3 months and 33.7% at 12 months.
CONCLUSION: Our findings are in line with existing evidence. Questions regarding persistence of gait- and balance-related side effects remain.