Efficacy of colchicine in oral submucous fibrosis: A systematic review and meta-analysis.

One of the potentially malignant disorders of the oral mucosa in Asian nations is known as oral submucous fibrosis (OSMF). The drug, surgical and combination therapies are some of the several OSMF treatment options. The importance of colchicine in the treatment of oral submucous fibrosis is still unclear. Therefore, it is of interest to review the efficacy of colchicine in oral submucous fibrosis in terms of improving symptoms such as burning sensation and mouth opening. Known data shows colchicine is in alleviating these symptoms in OSMF patients.