[Study on diagnosis of chronic schistosomiasis japonicum with rSj26-Sj32 fusion protein].

AIM: To study whether rSj26-Sj32 fusion protein can be used for diagnosis of chronic schistosomiasis japonicum.

METHODS

ELISA, Dot-ELISA and dipstick were performed to detect the IgG in the sera of patients with chronic schistosomiasis japonicum using the antigens of rSj26-Sj32 fusion protein and SjAWA. The control sera were taken from health donors and the patients with clonorchiasis sinensis, paragonimiasis westermani, alveolar echinococcosis and cystic echinococcosis.

RESULTS

The sensitivity of the three methods was 95.00%, 92.50% and 92.50% respectively, whereas the specificity of the three methods was 97.67%, 95.35% and 97.67%, respectively.

CONCLUSION

The rSj26-Sj32 fusion protein has therapeutic potential for immunodiagnosis of chronic schistosomiasis japonicum.