Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae · 2006
[Factors influencing the recurrence of Cushing's disease treated by transsphenoidal surgery].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Xia Xue-Wei, Su Chang-Bao, Ren Zu-Yuan, Wang Ren-Zhi, Yang Yi, Ma Wen-Bin, Li Yong-Ning, Kong Yan-Guo
Аннотация
OBJECTIVE: To explore factors influencing the recurrence of patients with Cushing's disease after transsphenoidal surgery.
METHODS: We retrospectively analyzed the clinical data of 182 patients treated by transsphenoidal surgery with Cushing's disease in our department in PUMC Hospital from 1992 to 2002.
RESULTS: The recurrence rates were significantly different when patients had different radiological findings (P = 0.001), operative methods (P = 0.001), histological findings (P = 0.04), and postoperative cortisol levels (P = 0.02); however, such difference was not found in term of tumor size (P = 0.43).
CONCLUSION: Radiological findings, operative methods, histological findings, and postoperative cortisol estimates may be the factors influencing the recurrence of patients treated by transsphenoidal surgery.
METHODS: We retrospectively analyzed the clinical data of 182 patients treated by transsphenoidal surgery with Cushing's disease in our department in PUMC Hospital from 1992 to 2002.
RESULTS: The recurrence rates were significantly different when patients had different radiological findings (P = 0.001), operative methods (P = 0.001), histological findings (P = 0.04), and postoperative cortisol levels (P = 0.02); however, such difference was not found in term of tumor size (P = 0.43).
CONCLUSION: Radiological findings, operative methods, histological findings, and postoperative cortisol estimates may be the factors influencing the recurrence of patients treated by transsphenoidal surgery.