Archives of physical medicine and rehabilitation · 2024
Comparison of the Efficacy of 2 Different Botulinum Toxin Injection Techniques in Gastrocnemius Muscle Spasticity in Hemiplegic Patients: A Randomized Double-Blind Controlled Study.
СтатьяРандомизированное исследованиеСравнительное исследованиеНазвание и аннотация: Перевод в очереди
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Karpuz Savaş, Yılmaz Ramazan, Yılmaz Halim
Аннотация
OBJECTIVE: To compare the efficacy of the innervation zone-targeted injection technique (EUROMUSCULUS/USPRM (Ultrasound Study Group of the International Society of Physical and Rehabilitation Medicine) spasticity approach) and the injection technique along the muscle length.
DESIGN: A double-blind randomized controlled trial.
SETTING: Department of rehabilitation medicine of a medical center.
PARTICIPANTS: One hundred patients with stroke experiencing ankle plantar flexor spasticity.
INTERVENTIONS: In addition to conventional rehabilitation, eligible patients were randomly assigned to 2 groups. The experimental group was injected with botulinum toxin along the length of the muscle, whereas the control group was injected with the same dose and volume of botulinum toxin 25%-35% proximal to the medial head and 20%-30% proximal to the lateral aspect of the head of the gastrocnemius muscle.
MAIN OUTCOME MEASURES: Modified Ashworth scale, modified Tardieu scale, ankle range of motion measurement, and 10-meter walk test were used before and 1 month after injection.
RESULTS: The study was completed by 60 participants with a mean age of 59.96±12.15 years. Both injection methods were found to be effective on range of motion, spasticity level, ambulation, and walking speed. There was no statistically significant difference between injection methods.
CONCLUSIONS: Both injection methods of botulinum toxin A produce similar clinical effects.
DESIGN: A double-blind randomized controlled trial.
SETTING: Department of rehabilitation medicine of a medical center.
PARTICIPANTS: One hundred patients with stroke experiencing ankle plantar flexor spasticity.
INTERVENTIONS: In addition to conventional rehabilitation, eligible patients were randomly assigned to 2 groups. The experimental group was injected with botulinum toxin along the length of the muscle, whereas the control group was injected with the same dose and volume of botulinum toxin 25%-35% proximal to the medial head and 20%-30% proximal to the lateral aspect of the head of the gastrocnemius muscle.
MAIN OUTCOME MEASURES: Modified Ashworth scale, modified Tardieu scale, ankle range of motion measurement, and 10-meter walk test were used before and 1 month after injection.
RESULTS: The study was completed by 60 participants with a mean age of 59.96±12.15 years. Both injection methods were found to be effective on range of motion, spasticity level, ambulation, and walking speed. There was no statistically significant difference between injection methods.
CONCLUSIONS: Both injection methods of botulinum toxin A produce similar clinical effects.